Study Says Only Men May Benefit From Implantable Heart Devices
Published On: September 15th, 2009
Implantable cardioverter defibrillators — expensive devices that monitor the heart for irregular beating and shocks it back to its normal rhythm — don’t appear effective in women, a newly published analysis of pooled data shows.
Though 30% of ICDs are implanted in women, there isn’t much evidence that these devices help prevent death in women with heart failure, according to the authors of the study, which was published in the Archives of Internal Medicine.
The meta-analysis examined data from 934 women and 3,810 men across five clinical trials. The results indicated there wasn’t a statistically significant benefit of implanting an ICD in women. Men who received the device, however, were less likely to die in the followup period after the procedure compared with men who received medication treatments.
Another recent study found that women have a 70% greater risk of major adverse events after ICD implantation than men, Rita Redberg, editor of the Archives, wrote in an editorial accompanying the meta-analysis.
“In other words, ICDs are being implanted in hundreds of thousands of women without substantial evidence of benefit, apparently based on the assumption that, to paraphrase the old saying, ‘What’s good for the gander is good for the goose,’ ” writes Redberg in her editorial.
The authors of the Archives study conclude that “most clinical trials have been heavily weighted toward men; therefore, generalization of the results to women remains questionable.” The best way of answering the question of ICD effectiveness in women is to conduct a clinical trial that specifically focuses on their use in women with heart failure, they say.
Image courtesy of Columbia University Medical Center
Here is the original:
Study Says Only Men May Benefit From Implantable Heart Devices
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